Insights gained from single-cell analysis of immune cells in tofacitinib treatment of Vogt-Koyanagi-Harada disease

Vogt-Koyanagi-Harada disease (VKH) is an important refractory uveitis mediated by pathological T cells (TCs). Tofacitinib (TOFA) is a JAK- targeted therapy for several autoimmune diseases. However, the specific pathogenesis and targeted therapeutics for VKH remain largely unknown. Based on single-ce...

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Detalles Bibliográficos
Autores principales: Liu, Xiuxing, Jiang, Qi, Lv, Jianjie, Yang, Shizhao, Huang, Zhaohao, Duan, Runping, Tao, Tianyu, Li, Zhaohuai, Ju, Rong, Zheng, Yingfeng, Su, Wenru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9746911/
https://www.ncbi.nlm.nih.gov/pubmed/36301664
http://dx.doi.org/10.1172/jci.insight.162335

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9746911/
https://www.ncbi.nlm.nih.gov/pubmed/36301664
http://dx.doi.org/10.1172/jci.insight.162335

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