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Structural basis for matriglycan synthesis by the LARGE1 dual glycosyltransferase

LARGE1 is a bifunctional glycosyltransferase responsible for generating a long linear polysaccharide termed matriglycan that links the cytoskeleton and the extracellular matrix and is required for proper muscle function. This matriglycan polymer is made with an alternating pattern of xylose and gluc...

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Detalles Bibliográficos
Autores principales: Katz, Michael, Diskin, Ron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9746966/
https://www.ncbi.nlm.nih.gov/pubmed/36512577
http://dx.doi.org/10.1371/journal.pone.0278713