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Structural basis for matriglycan synthesis by the LARGE1 dual glycosyltransferase
LARGE1 is a bifunctional glycosyltransferase responsible for generating a long linear polysaccharide termed matriglycan that links the cytoskeleton and the extracellular matrix and is required for proper muscle function. This matriglycan polymer is made with an alternating pattern of xylose and gluc...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9746966/ https://www.ncbi.nlm.nih.gov/pubmed/36512577 http://dx.doi.org/10.1371/journal.pone.0278713 |