ERK1/2 signalling dynamics promote neural differentiation by regulating chromatin accessibility and the polycomb repressive complex

Fibroblast growth factor (FGF) is a neural inducer in many vertebrate embryos, but how it regulates chromatin organization to coordinate the activation of neural genes is unclear. Moreover, for differentiation to progress, FGF signalling must decline. Why these signalling dynamics are required has n...

Descripción completa

Detalles Bibliográficos
Autores principales: Semprich, Claudia I., Davidson, Lindsay, Amorim Torres, Adriana, Patel, Harshil, Briscoe, James, Metzis, Vicki, Storey, Kate G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9746999/
https://www.ncbi.nlm.nih.gov/pubmed/36455041
http://dx.doi.org/10.1371/journal.pbio.3000221

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9746999/
https://www.ncbi.nlm.nih.gov/pubmed/36455041
http://dx.doi.org/10.1371/journal.pbio.3000221

Ejemplares similares