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ERK1/2 signalling dynamics promote neural differentiation by regulating chromatin accessibility and the polycomb repressive complex
Fibroblast growth factor (FGF) is a neural inducer in many vertebrate embryos, but how it regulates chromatin organization to coordinate the activation of neural genes is unclear. Moreover, for differentiation to progress, FGF signalling must decline. Why these signalling dynamics are required has n...
Autores principales: | Semprich, Claudia I., Davidson, Lindsay, Amorim Torres, Adriana, Patel, Harshil, Briscoe, James, Metzis, Vicki, Storey, Kate G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9746999/ https://www.ncbi.nlm.nih.gov/pubmed/36455041 http://dx.doi.org/10.1371/journal.pbio.3000221 |
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