APOE alleles are associated with sex-specific structural differences in brain regions affected in Alzheimer’s disease and related dementia

Alzheimer’s disease is marked by intracellular tau aggregates in the medial temporal lobe (MTL) and extracellular amyloid aggregates in the default network (DN). Here, we examined codependent structural variations between the MTL’s most vulnerable structure, the hippocampus (HC), and the DN at subre...

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Detalles Bibliográficos
Autores principales: Savignac, Chloé, Villeneuve, Sylvia, Badhwar, AmanPreet, Saltoun, Karin, Shafighi, Kimia, Zajner, Chris, Sharma, Vaibhav, Gagliano Taliun, Sarah A., Farhan, Sali, Poirier, Judes, Bzdok, Danilo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9747055/
https://www.ncbi.nlm.nih.gov/pubmed/36512526
http://dx.doi.org/10.1371/journal.pbio.3001863

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9747055/
https://www.ncbi.nlm.nih.gov/pubmed/36512526
http://dx.doi.org/10.1371/journal.pbio.3001863

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