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Population‐based cellular kinetic characterization of ciltacabtagene autoleucel in subjects with relapsed or refractory multiple myeloma

The aims of this work were to develop a population pharmacokinetic (PK) model for chimeric antigen receptor (CAR) transgene after single intravenous infusion administration of ciltacabtagene autoleucel in adult patients with relapsed or refractory multiple myeloma. CAR transgene level in blood were...

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Detalles Bibliográficos
Autores principales: Wu, Liviawati S., Su, Yaming, Li, Claire, Zhou, Wangda, Jackson, Carolyn C., Sun, Yu‐Nien, Zhou, Honghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9747118/
https://www.ncbi.nlm.nih.gov/pubmed/36204820
http://dx.doi.org/10.1111/cts.13421