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Association of Vitamin D Polygenic Risk Scores and Disease Outcome in People With Multiple Sclerosis

BACKGROUND AND OBJECTIVES: Observational studies suggest low levels of 25-hydroxyvitamin D (25[OH]D) may be associated with increased disease activity in people with multiple sclerosis (PwMS). Large-scale genome-wide association studies (GWAS) suggest 25(OH)D levels are partly genetically determined...

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Detalles Bibliográficos
Autores principales: Vasileiou, Eleni S., Hu, Chen, Bernstein, Charles N., Lublin, Fred, Wolinsky, Jerry S., Cutter, Gary R., Sotirchos, Elias S., Kowalec, Kaarina, Salter, Amber, Saidha, Shiv, Mowry, Ellen M., Calabresi, Peter A., Marrie, Ruth Ann, Fitzgerald, Kathryn C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9747144/
https://www.ncbi.nlm.nih.gov/pubmed/36418179
http://dx.doi.org/10.1212/NXI.0000000000200062