Evidence linking APOBEC3B genesis and evolution of innate immune antagonism by gamma-herpesvirus ribonucleotide reductases

Viruses have evolved diverse mechanisms to antagonize host immunity such as direct inhibition and relocalization of cellular APOBEC3B (A3B) by the ribonucleotide reductase (RNR) of Epstein-Barr virus. Here, we investigate the mechanistic conservation and evolutionary origin of this innate immune cou...

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Detalles Bibliográficos
Autores principales: Moraes, Sofia N, Becker, Jordan T, Moghadasi, Seyed Arad, Shaban, Nadine M, Auerbach, Ashley A, Cheng, Adam Z, Harris, Reuben S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Evolutionary Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9747160/
https://www.ncbi.nlm.nih.gov/pubmed/36458685
http://dx.doi.org/10.7554/eLife.83893

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9747160/
https://www.ncbi.nlm.nih.gov/pubmed/36458685
http://dx.doi.org/10.7554/eLife.83893

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