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Genetic polymorphisms and their effects on the severity of silicosis in workers exposed to silica in Brazil

OBJECTIVE: Silicosis is a pneumoconiosis characterized by fibrosis of the lung parenchyma caused by inhalation of silica particles. Genetic factors might play a role in the severity silicosis. We sought to evaluate the influence of polymorphisms in the ACE, FAS, FASLG, NOS2, IL1RN, FAM13A, TGFB1, an...

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Detalles Bibliográficos
Autores principales: de Castro, Marcos César Santos, Nani, Angela Santos Ferreira, Salum, Kaio Cezar Rodrigues, Rolando, Jônatas de Mendonça, dos Santos, Júlia Fernandes Barbosa, de Castro, Hermano Albuquerque, Ribeiro, Patrícia Canto, Costa, Walter, de Mello, Cícero Brasileiro, Kohlrausch, Fabiana Barzotto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Pneumologia e Tisiologia 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9747185/
https://www.ncbi.nlm.nih.gov/pubmed/36350953
http://dx.doi.org/10.36416/1806-3756/e20220167