Targeting the STAT5A/IDO1 axis overcomes radioresistance and reverses the immunosuppressive tumor microenvironment in NSCLC

As a metabolic mediator of antitumor immunity, indoleamine-2,3-dioxygenase 1 (IDO1) is upregulated in various types of cancer; however, the regulatory mechanism and clinical significance of IDO1 in non-small cell lung cancer (NSCLC) radiotherapy (RT) remain unclear. The present study investigated th...

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Detalles Bibliográficos
Autores principales: Yang, Yang, Zheng, Xiaoli, Ni, Peizan, Li, Dingjie, Dan, Qinfu, Wang, Xiaohui, Wang, Yunhan, Sun, Yanan, Liu, Kangdong, Dong, Zigang, Ge, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9747191/
https://www.ncbi.nlm.nih.gov/pubmed/36453241
http://dx.doi.org/10.3892/ijo.2022.5460

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9747191/
https://www.ncbi.nlm.nih.gov/pubmed/36453241
http://dx.doi.org/10.3892/ijo.2022.5460

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