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Human B-1 cells are important contributors to the naturally-occurring IgM pool against the tumor-associated ganglioside Neu5GcGM3

Only few studies have described the anti-tumor properties of natural antibodies (NAbs). In particular, natural IgM have been linked to cancer immunosurveillance due to its preferential binding to tumor-specific glycolipids and carbohydrate structures. Neu5GcGM3 ganglioside is a sialic acid–containin...

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Detalles Bibliográficos
Autores principales: Rodriguez-Zhurbenko, Nely, Quach, Tam D., Rothstein, Thomas L., Hernandez, Ana M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9747505/
https://www.ncbi.nlm.nih.gov/pubmed/36524112
http://dx.doi.org/10.3389/fimmu.2022.1061651