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Integrative bioinformatic analysis of p53 and pathway alterations in two different lung cancer subtypes
Whether p53, either wild type (WT) or mutant, plays cell-specific or uniform role remains controversial. Using The Cancer Genome Atlas, we examined p53 in the lung adenocarcinoma (LUAD) and lung squamous cell carcinoma (LUSC), two lung cancers with different cellular origins and frequent p53 mutatio...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9747529/ https://www.ncbi.nlm.nih.gov/pubmed/36532876 http://dx.doi.org/10.1016/j.bbrep.2022.101404 |