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Interleukin-27 impairs BCG antigen clearance and T cell stimulatory potential by neonatal dendritic cells
Bacille Calmette Guérin (BCG) is a live-attenuated vaccine for protection against Mycobacterium tuberculosis. Despite high disease protection in infancy and early childhood, it generates poor long-term protection against pulmonary tuberculosis. We hypothesized that the unique immune profile that inc...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9747568/ https://www.ncbi.nlm.nih.gov/pubmed/36530844 http://dx.doi.org/10.1016/j.crmicr.2022.100176 |