Fungal sensing by dectin-1 directs the non-pathogenic polarization of T(H)17 cells through balanced type I IFN responses in human DCs

The non-pathogenic T(H)17 subset of helper T cells clears fungal infections, whereas pathogenic T(H)17 cells cause inflammation and tissue damage; however, the mechanisms controlling these distinct responses remain unclear. Here we found that fungi sensing by the C-type lectin dectin-1 in human dend...

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Detalles Bibliográficos
Autores principales: Gringhuis, Sonja I., Kaptein, Tanja M., Remmerswaal, Ester B. M., Drewniak, Agata, Wevers, Brigitte A., Theelen, Bart, D’Haens, Geert R. A. M., Boekhout, Teun, Geijtenbeek, Teunis B. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9747615/
https://www.ncbi.nlm.nih.gov/pubmed/36456734
http://dx.doi.org/10.1038/s41590-022-01348-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9747615/
https://www.ncbi.nlm.nih.gov/pubmed/36456734
http://dx.doi.org/10.1038/s41590-022-01348-2

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