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Fungal sensing by dectin-1 directs the non-pathogenic polarization of T(H)17 cells through balanced type I IFN responses in human DCs
The non-pathogenic T(H)17 subset of helper T cells clears fungal infections, whereas pathogenic T(H)17 cells cause inflammation and tissue damage; however, the mechanisms controlling these distinct responses remain unclear. Here we found that fungi sensing by the C-type lectin dectin-1 in human dend...
Autores principales: | Gringhuis, Sonja I., Kaptein, Tanja M., Remmerswaal, Ester B. M., Drewniak, Agata, Wevers, Brigitte A., Theelen, Bart, D’Haens, Geert R. A. M., Boekhout, Teun, Geijtenbeek, Teunis B. H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9747615/ https://www.ncbi.nlm.nih.gov/pubmed/36456734 http://dx.doi.org/10.1038/s41590-022-01348-2 |
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