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Parenteral BCG vaccine induces lung-resident memory macrophages and trained immunity via the gut–lung axis

Aside from centrally induced trained immunity in the bone marrow (BM) and peripheral blood by parenteral vaccination or infection, evidence indicates that mucosal-resident innate immune memory can develop via a local inflammatory pathway following mucosal exposure. However, whether mucosal-resident...

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Detalles Bibliográficos
Autores principales: Jeyanathan, Mangalakumari, Vaseghi-Shanjani, Maryam, Afkhami, Sam, Grondin, Jensine A., Kang, Alisha, D’Agostino, Michael R., Yao, Yushi, Jain, Shreya, Zganiacz, Anna, Kroezen, Zachary, Shanmuganathan, Meera, Singh, Ramandeep, Dvorkin-Gheva, Anna, Britz-McKibbin, Philip, Khan, Waliul I., Xing, Zhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9747617/
https://www.ncbi.nlm.nih.gov/pubmed/36456739
http://dx.doi.org/10.1038/s41590-022-01354-4