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Parenteral BCG vaccine induces lung-resident memory macrophages and trained immunity via the gut–lung axis
Aside from centrally induced trained immunity in the bone marrow (BM) and peripheral blood by parenteral vaccination or infection, evidence indicates that mucosal-resident innate immune memory can develop via a local inflammatory pathway following mucosal exposure. However, whether mucosal-resident...
Autores principales: | Jeyanathan, Mangalakumari, Vaseghi-Shanjani, Maryam, Afkhami, Sam, Grondin, Jensine A., Kang, Alisha, D’Agostino, Michael R., Yao, Yushi, Jain, Shreya, Zganiacz, Anna, Kroezen, Zachary, Shanmuganathan, Meera, Singh, Ramandeep, Dvorkin-Gheva, Anna, Britz-McKibbin, Philip, Khan, Waliul I., Xing, Zhou |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9747617/ https://www.ncbi.nlm.nih.gov/pubmed/36456739 http://dx.doi.org/10.1038/s41590-022-01354-4 |
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