Glucagon changes substrate preference in gluconeogenesis

Fasting hyperglycemia in diabetes mellitus is caused by unregulated glucagon secretion that activates gluconeogenesis (GNG) and increases the use of pyruvate, lactate, amino acids, and glycerol. Studies of GNG in hepatocytes, however, tend to test a limited number of substrates at nonphysiologic con...

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Detalles Bibliográficos
Autores principales: Xu, Huiting, Wang, Yujue, Kwon, Hyokjoon, Shah, Ankit, Kalemba, Katarzyna, Su, Xiaoyang, He, Ling, Wondisford, Fredric E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9747632/
https://www.ncbi.nlm.nih.gov/pubmed/36402444
http://dx.doi.org/10.1016/j.jbc.2022.102708

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9747632/
https://www.ncbi.nlm.nih.gov/pubmed/36402444
http://dx.doi.org/10.1016/j.jbc.2022.102708

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