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DCZ19931, a novel multi-targeting kinase inhibitor, inhibits ocular neovascularization

Neovascularization is a prominent cause of irreversible blindness in a variety of ocular diseases. Current therapies for pathological neovascularization are concentrated on the suppression of vascular endothelial growth factors (VEGF). Despite the remarkable efficacy of anti-VEGF drugs, several prob...

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Detalles Bibliográficos
Autores principales: Zhang, Huiying, Li, Bo, Ding, Jingjuan, Ye, Rong, Xu, Zhijian, Zhang, Qiuyang, Feng, Siguo, Jiang, Qin, Zhu, Weiliang, Yan, Biao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9747701/
https://www.ncbi.nlm.nih.gov/pubmed/36513701
http://dx.doi.org/10.1038/s41598-022-25811-0