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Activation of a transient progenitor state in the epicardium is required for zebrafish heart regeneration

The epicardium, a mesothelial cell tissue that encompasses vertebrate hearts, supports heart regeneration after injury through paracrine effects and as a source of multipotent progenitors. However, the progenitor state in the adult epicardium has yet to be defined. Through single-cell RNA-sequencing...

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Detalles Bibliográficos
Autores principales: Xia, Yu, Duca, Sierra, Perder, Björn, Dündar, Friederike, Zumbo, Paul, Qiu, Miaoyan, Yao, Jun, Cao, Yingxi, Harrison, Michael R. M., Zangi, Lior, Betel, Doron, Cao, Jingli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9747719/
https://www.ncbi.nlm.nih.gov/pubmed/36513650
http://dx.doi.org/10.1038/s41467-022-35433-9