Kinesin-5 Eg5 is essential for spindle assembly, chromosome stability and organogenesis in development

Chromosome stability relies on bipolar spindle assembly and faithful chromosome segregation during cell division. Kinesin-5 Eg5 is a plus-end-directed kinesin motor protein, which is essential for spindle pole separation and chromosome alignment in mitosis. Heterozygous Eg5 mutations cause autosomal...

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Detalles Bibliográficos
Autores principales: Yu, Wen-Xin, Li, Yu-Kun, Xu, Meng-Fei, Xu, Chen-Jie, Chen, Jie, Wei, Ya-Lan, She, Zhen-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9747790/
https://www.ncbi.nlm.nih.gov/pubmed/36513626
http://dx.doi.org/10.1038/s41420-022-01281-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9747790/
https://www.ncbi.nlm.nih.gov/pubmed/36513626
http://dx.doi.org/10.1038/s41420-022-01281-1

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