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Metformin enhances the antitumor activity of oncolytic herpes simplex virus HF10 (canerpaturev) in a pancreatic cell cancer subcutaneous model

Oncolytic virus (OV) therapy is a promising cancer immunotherapy, especially for cold tumors by inducing the direct lysis of cancer cells and initiation of potent antitumor response. Canerpaturev (C-REV) is an attenuated oncolytic herpes simplex virus-1, which demonstrated a potent antitumor effect...

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Detalles Bibliográficos
Autores principales: Abdelmoneim, Mohamed, Eissa, Ibrahim Ragab, Aboalela, Mona Alhussein, Naoe, Yoshinori, Matsumura, Shigeru, Sibal, Patricia Angela, Bustos-Villalobos, Itzel, Tanaka, Maki, Kodera, Yasuhiro, Kasuya, Hideki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9747797/
https://www.ncbi.nlm.nih.gov/pubmed/36513720
http://dx.doi.org/10.1038/s41598-022-25065-w