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Loss of the Ash2l subunit of histone H3K4 methyltransferase complexes reduces chromatin accessibility at promoters

Changes in gene expression programs are intimately linked to cell fate decisions. Post-translational modifications of core histones contribute to control gene expression. Methylation of lysine 4 of histone H3 (H3K4) correlates with active promoters and gene transcription. This modification is cataly...

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Detalles Bibliográficos
Autores principales: Barsoum, Mirna, Stenzel, Alexander T., Bochyńska, Agnieszka, Kuo, Chao-Chung, Tsompanidis, Alexander, Sayadi-Boroujeni, Roksaneh, Bussmann, Philip, Lüscher-Firzlaff, Juliane, Costa, Ivan G., Lüscher, Bernhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9747801/
https://www.ncbi.nlm.nih.gov/pubmed/36513698
http://dx.doi.org/10.1038/s41598-022-25881-0