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Novel preclinical gastroenteropancreatic neuroendocrine neoplasia models demonstrate the feasibility of mutation-based targeted therapy

PURPOSE: Gastroenteropancreatic neuroendocrine neoplasms (GEP-NEN) form a rare and remarkably heterogeneous group of tumors. Therefore, establishing personalized therapies is eminently challenging. To achieve progress in preclinical drug development, there is an urgent need for relevant tumor models...

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Detalles Bibliográficos
Autores principales: Viol, Fabrice, Sipos, Bence, Fahl, Martina, Clauditz, Till S., Amin, Tania, Kriegs, Malte, Nieser, Maike, Izbicki, Jakob R., Huber, Samuel, Lohse, Ansgar W., Schrader, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9747820/
https://www.ncbi.nlm.nih.gov/pubmed/36269546
http://dx.doi.org/10.1007/s13402-022-00727-z