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Novel preclinical gastroenteropancreatic neuroendocrine neoplasia models demonstrate the feasibility of mutation-based targeted therapy
PURPOSE: Gastroenteropancreatic neuroendocrine neoplasms (GEP-NEN) form a rare and remarkably heterogeneous group of tumors. Therefore, establishing personalized therapies is eminently challenging. To achieve progress in preclinical drug development, there is an urgent need for relevant tumor models...
Autores principales: | Viol, Fabrice, Sipos, Bence, Fahl, Martina, Clauditz, Till S., Amin, Tania, Kriegs, Malte, Nieser, Maike, Izbicki, Jakob R., Huber, Samuel, Lohse, Ansgar W., Schrader, Jörg |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9747820/ https://www.ncbi.nlm.nih.gov/pubmed/36269546 http://dx.doi.org/10.1007/s13402-022-00727-z |
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