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Low-dose anti-VEGFR2 therapy promotes anti-tumor immunity in lung adenocarcinoma by down-regulating the expression of layilin on tumor-infiltrating CD8(+)T cells

PURPOSE: Our study intended to explore how low-dose anti-angiogenic drugs affected anti-tumor immunity of tumor-infiltrating exhausted CD8(+)T cells and achieved better clinical response when combined with immunotherapy. We set out to find potential targets or predictive biomarker on CD8(+)T cells f...

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Detalles Bibliográficos
Autores principales: Yang, Biaolong, Deng, Biaolong, Jiao, Xiao-Dong, Qin, Bao-Dong, Lu, Yi, Zhang, Weiqi, Guo, Yixian, Chen, Shiqi, Li, Dan, Li, Bin, Zang, Yuan-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9747853/
https://www.ncbi.nlm.nih.gov/pubmed/36260222
http://dx.doi.org/10.1007/s13402-022-00718-0