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Low-dose anti-VEGFR2 therapy promotes anti-tumor immunity in lung adenocarcinoma by down-regulating the expression of layilin on tumor-infiltrating CD8(+)T cells
PURPOSE: Our study intended to explore how low-dose anti-angiogenic drugs affected anti-tumor immunity of tumor-infiltrating exhausted CD8(+)T cells and achieved better clinical response when combined with immunotherapy. We set out to find potential targets or predictive biomarker on CD8(+)T cells f...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9747853/ https://www.ncbi.nlm.nih.gov/pubmed/36260222 http://dx.doi.org/10.1007/s13402-022-00718-0 |