ABCA6 affects the malignancy of Ewing sarcoma cells via cholesterol-guided inhibition of the IGF1R/AKT/MDM2 axis

PURPOSE: The relevance of the subfamily A members of ATP-binding cassette (ABCA) transporters as biomarkers of risk and response is emerging in different tumors, but their mechanisms of action have only been partially defined. In this work, we investigated their role in Ewing sarcoma (EWS), a pediat...

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Detalles Bibliográficos
Autores principales: Pasello, Michela, Giudice, Anna Maria, Cristalli, Camilla, Manara, Maria Cristina, Mancarella, Caterina, Parra, Alessandro, Serra, Massimo, Magagnoli, Giovanna, Cidre-Aranaz, Florencia, Grünewald, Thomas G. P., Bini, Carla, Lollini, Pier-Luigi, Longhi, Alessandra, Donati, Davide Maria, Scotlandi, Katia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9747862/
https://www.ncbi.nlm.nih.gov/pubmed/36149602
http://dx.doi.org/10.1007/s13402-022-00713-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9747862/
https://www.ncbi.nlm.nih.gov/pubmed/36149602
http://dx.doi.org/10.1007/s13402-022-00713-5

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