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Proteomic characterisation of prostate cancer intercellular communication reveals cell type-selective signalling and TMSB4X-dependent fibroblast reprogramming

BACKGROUND: In prostate cancer, the tumour microenvironment (TME) represents an important regulator of disease progression and response to treatment. In the TME, cancer-associated fibroblasts (CAFs) play a key role in tumour progression, however the mechanisms underpinning fibroblast-cancer cell int...

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Detalles Bibliográficos
Autores principales: Wu, Yunjian, Clark, Kimberley C., Nguyen, Elizabeth V., Niranjan, Birunthi, Horvath, Lisa G., Taylor, Renea A., Daly, Roger J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9747870/
https://www.ncbi.nlm.nih.gov/pubmed/36169805
http://dx.doi.org/10.1007/s13402-022-00719-z