Cargando…

AMPKα2 controls the anti-atherosclerotic effects of fish oils by modulating the SUMOylation of GPR120

Consuming fish oils (FO) is linked to reduced risk of cardiovascular disease in certain populations. However, FO failed to exhibit therapeutic effects in some patients with cardiovascular disease. This study aimed to determine the possible reasons for the inconsistent effects of FO. AMP-activated pr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yan, Cheng-hui, Liu, Hai-Wei, Tian, Xiao-xiang, Li, Jiayin, Ding, Ye, Li, Yi, Mei, Zhu, Zou, Ming-Hui, Han, Ya-ling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9747961/ https://www.ncbi.nlm.nih.gov/pubmed/36513627 http://dx.doi.org/10.1038/s41467-022-34996-x

Ejemplares similares

Fish Oil Accelerates Diet-Induced Entrainment of the Mouse Peripheral Clock via GPR120
por: Furutani, Akiko, et al.
Publicado: (2015)

Polymorphisms in FFAR4 (GPR120) Gene Modulate Insulin Levels and Sensitivity after Fish Oil Supplementation
por: Vallée Marcotte, Bastien, et al.
Publicado: (2017)

Regulation of Energy Homeostasis via GPR120
por: Ichimura, Atsuhiko, et al.
Publicado: (2014)

GPR120 is an important inflammatory regulator in the development of osteoarthritis
por: Chen, Yuanfeng, et al.
Publicado: (2018)

The protease SENP2 controls hepatic gluconeogenesis by regulating the SUMOylation of the fuel sensor AMPKα
por: Dou, Xin, et al.
Publicado: (2021)

FFA4/GPR120: Pharmacology and Therapeutic Opportunities
por: Milligan, Graeme, et al.
Publicado: (2017)

GPR120 promotes neutrophil control of intestinal bacterial infection
por: Zhou, Zheng, et al.
Publicado: (2023)

SUMOylation of AMPKα1 by PIAS4 specifically regulates mTORC1 signalling
por: Yan, Yan, et al.
Publicado: (2015)

The GPR120 Agonist TUG-891 Inhibits the Motility and Phagocytosis of Mouse Alveolar Macrophages
por: Su, Xing-Li, et al.
Publicado: (2020)

GPR120: A bi-potential mediator to modulate the osteogenic and adipogenic differentiation of BMMSCs
por: Gao, Bo, et al.
Publicado: (2015)

Potential roles of GPR120 and its agonists in the management of diabetes
por: Zhang, Dan, et al.
Publicado: (2014)

Identification of Crocetin as a Dual Agonist of GPR40 and GPR120 Responsible for the Antidiabetic Effect of Saffron
por: Zhao, Xiaodi, et al.
Publicado: (2023)

Fluorescent Ligand-Based Discovery of Small-Molecule Sulfonamide Agonists for GPR120
por: Ma, Siyue, et al.
Publicado: (2022)

Omega-3 from Flaxseed Oil Protects Obese Mice Against Diabetic Retinopathy Through GPR120 Receptor
por: Dátilo, Marcella Neves, et al.
Publicado: (2018)

Polyunsaturated fatty acid receptors, GPR40 and GPR120, are expressed in the hypothalamus and control energy homeostasis and inflammation
por: Dragano, Nathalia R. V., et al.
Publicado: (2017)

A High-Fat Diet Attenuates AMPK α1 in Adipocytes to Induce Exosome Shedding and Nonalcoholic Fatty Liver Development In Vivo
por: Yan, Chenghui, et al.
Publicado: (2021)

Docosahexaenoic acid inhibits TNF-α-induced osteoclast formation and orthodontic tooth movement through GPR120
por: Ma, Jinghan, et al.
Publicado: (2023)

The Role of GPR120 Receptor in Essential Fatty Acids Metabolism in Schizophrenia
por: Rog, Joanna, et al.
Publicado: (2020)

Discovery of Novel and Selective G-Protein Coupled Receptor 120 (GPR120) Agonists for the Treatment of Type 2 Diabetes Mellitus
por: Wang, Xuekun, et al.
Publicado: (2022)

Author Correction: GPR120: A bi-potential mediator to modulate the osteogenic and adipogenic differentiation of BMMSCs
por: Gao, Bo, et al.
Publicado: (2020)

GPR120 Agonist GW9508 Ameliorated Cellular Senescence Induced by ox-LDL
por: Liu, Ruijie, et al.
Publicado: (2020)

A Gpr120 Selective Agonist Improves Insulin Resistance and Chronic Inflammation
por: Oh, Da Young, et al.
Publicado: (2014)

Thiazolidinedione derivatives as novel GPR120 agonists for the treatment of type 2 diabetes
por: Wang, Xuekun, et al.
Publicado: (2022)

GPR120 prevents colorectal adenocarcinoma progression by sustaining the mucosal barrier integrity
por: Rubbino, Federica, et al.
Publicado: (2022)

GPR120 modulates epileptic seizure and neuroinflammation mediated by NLRP3 inflammasome
por: Qin, Zhangjin, et al.
Publicado: (2022)

Predictive value of first-trimester GPR120 levels in gestational diabetes mellitus
por: He, Qingwen, et al.
Publicado: (2023)

Molecular docking and identification of G-protein-coupled receptor 120 (GPR120) agonists as SARS COVID-19 MPro inhibitors
por: Mohan, Sellappan, et al.
Publicado: (2022)

Erratum. A High-Fat Diet Attenuates AMPK α1 in Adipocytes to Induce Exosome Shedding and Nonalcoholic Fatty Liver Development In Vivo. Diabetes 2021;70:577–588
por: Yan, Chenghui, et al.
Publicado: (2021)

GPR43 deficiency protects against podocyte insulin resistance in diabetic nephropathy through the restoration of AMPKα activity
por: Lu, Jian, et al.
Publicado: (2021)

Sumoylation Regulates Nuclear Localization of Lipin-1α in Neuronal Cells
por: Liu, Guang-Hui, et al.
Publicado: (2009)

Genetic variants of the unsaturated fatty acid receptor GPR120 relating to obesity in dogs
por: MIYABE, Masahiro, et al.
Publicado: (2015)

EPA Prevents the Development of Abdominal Aortic Aneurysms through Gpr-120/Ffar-4
por: Kamata, Ryo, et al.
Publicado: (2016)

A new insight into identification of in silico analysis of natural compounds targeting GPR120
por: Chinthakunta, Nagaraju, et al.
Publicado: (2018)

Revisiting PPARγ as a new friend of GPR120 in the treatment of metabolic disorders
por: Paschoal, Vivian A., et al.
Publicado: (2020)

Novel GPR120 Agonists with Improved Pharmacokinetic Profiles for the Treatment of Type 2 Diabetes
por: Ji, Guoxia, et al.
Publicado: (2021)

GPR120 induces regulatory dendritic cells by inhibiting HK2-dependent glycolysis to alleviate fulminant hepatic failure
por: Yu, Hongshuang, et al.
Publicado: (2021)

SUMOylation in α-Synuclein Homeostasis and Pathology
por: Savyon, Mor, et al.
Publicado: (2020)

Expression of the Fatty Acid Receptors GPR84 and GPR120 and Cytodifferentiation of Epithelial Cells in the Gastric Mucosa of Mouse Pups in the Course of Dietary Transition
por: Widmayer, Patricia, et al.
Publicado: (2017)

Sumoylation of AMPKβ2 subunit enhances AMP-activated protein kinase activity
por: Rubio, Teresa, et al.
Publicado: (2013)

Fish oil alleviates liver injury induced by intestinal ischemia/reperfusion via AMPK/SIRT-1/autophagy pathway
por: Jing, Hui-Rong, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_esn9bkiqv7fujov468c9s79mo1