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Condensates formed by prion-like low-complexity domains have small-world network structures and interfaces defined by expanded conformations

Biomolecular condensates form via coupled associative and segregative phase transitions of multivalent associative macromolecules. Phase separation coupled to percolation is one example of such transitions. Here, we characterize molecular and mesoscale structural descriptions of condensates formed b...

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Detalles Bibliográficos
Autores principales: Farag, Mina, Cohen, Samuel R., Borcherds, Wade M., Bremer, Anne, Mittag, Tanja, Pappu, Rohit V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9748015/
https://www.ncbi.nlm.nih.gov/pubmed/36513655
http://dx.doi.org/10.1038/s41467-022-35370-7