Cargando…
Condensates formed by prion-like low-complexity domains have small-world network structures and interfaces defined by expanded conformations
Biomolecular condensates form via coupled associative and segregative phase transitions of multivalent associative macromolecules. Phase separation coupled to percolation is one example of such transitions. Here, we characterize molecular and mesoscale structural descriptions of condensates formed b...
Autores principales: | Farag, Mina, Cohen, Samuel R., Borcherds, Wade M., Bremer, Anne, Mittag, Tanja, Pappu, Rohit V. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9748015/ https://www.ncbi.nlm.nih.gov/pubmed/36513655 http://dx.doi.org/10.1038/s41467-022-35370-7 |
Ejemplares similares
-
Phase Separation in Mixtures of Prion-Like Low Complexity Domains is Driven by the Interplay of Homotypic and Heterotypic Interactions
por: Pappu, Rohit, et al.
Publicado: (2023) -
Deciphering how naturally occurring sequence features impact the phase behaviors of disordered prion-like domains
por: Bremer, Anne, et al.
Publicado: (2022) -
Phase separation of protein mixtures is driven by the interplay of homotypic and heterotypic interactions
por: Farag, Mina, et al.
Publicado: (2023) -
Quantifying Coexistence Concentrations in Multi-Component Phase-Separating Systems Using Analytical HPLC
por: Bremer, Anne, et al.
Publicado: (2022) -
Endocytic proteins with prion-like domains form viscoelastic condensates that enable membrane remodeling
por: Bergeron-Sandoval, Louis-Philippe, et al.
Publicado: (2021)