Transcriptomic differences between fibrotic and non-fibrotic testicular tissue reveal possible key players in Klinefelter syndrome-related testicular fibrosis

Klinefelter syndrome (KS; 47,XXY) affects 1–2 in 1000 males. Most men with KS suffer from an early germ cell loss and testicular fibrosis from puberty onwards. Mechanisms responsible for these processes remain unknown. Previous genomics studies on testis tissue from men with KS focused on germ cell...

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Detalles Bibliográficos
Autores principales: Willems, Margo, Olsen, Catharina, Caljon, Ben, Vloeberghs, Veerle, De Schepper, Jean, Tournaye, Herman, Van Saen, Dorien, Goossens, Ellen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9748020/
https://www.ncbi.nlm.nih.gov/pubmed/36513788
http://dx.doi.org/10.1038/s41598-022-26011-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9748020/
https://www.ncbi.nlm.nih.gov/pubmed/36513788
http://dx.doi.org/10.1038/s41598-022-26011-6

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