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Transcriptomic differences between fibrotic and non-fibrotic testicular tissue reveal possible key players in Klinefelter syndrome-related testicular fibrosis
Klinefelter syndrome (KS; 47,XXY) affects 1–2 in 1000 males. Most men with KS suffer from an early germ cell loss and testicular fibrosis from puberty onwards. Mechanisms responsible for these processes remain unknown. Previous genomics studies on testis tissue from men with KS focused on germ cell...
Autores principales: | Willems, Margo, Olsen, Catharina, Caljon, Ben, Vloeberghs, Veerle, De Schepper, Jean, Tournaye, Herman, Van Saen, Dorien, Goossens, Ellen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9748020/ https://www.ncbi.nlm.nih.gov/pubmed/36513788 http://dx.doi.org/10.1038/s41598-022-26011-6 |
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