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Antidepressant-Like Activity of Solvent Fractions of the Root Bark of Carissa spinarum Linn. (Apocynaceae) in Rodents Involves Multiple Signaling Pathways

BACKGROUND: The root bark of Carissa spinarum Linn. (Apocynaceae) is claimed to be used for the management of depression in Ethiopian folkloric medicine, and the crude extract has been reported to possess antidepressant-like activity in rodents. OBJECTIVE: This study aimed to evaluate the antidepres...

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Detalles Bibliográficos
Autores principales: Ali, Hana Saif, Engidawork, Ephrem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9748120/
https://www.ncbi.nlm.nih.gov/pubmed/36531440
http://dx.doi.org/10.2147/JEP.S386015