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TNF-α and IL-1β Promote Renal Podocyte Injury in T2DM Rats by Decreasing Glomerular VEGF/eNOS Expression Levels and Altering Hemodynamic Parameters

PURPOSE: Diabetic nephropathy (DN) is a serious microvascular complication in those with type 2 diabetes mellitus (T2DM). Evidence confirms that serum tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β) in the T2DM stage are proposed as prognostic markers for DN development, but it is unclear...

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Detalles Bibliográficos
Autores principales: Wang, Jufang, Feng, Yating, Zhang, Yan, Liu, Jing, Gong, Le, Zhang, Xiaohong, Liao, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9748123/
https://www.ncbi.nlm.nih.gov/pubmed/36532651
http://dx.doi.org/10.2147/JIR.S391473