Selective Vulnerability of the Locus Coeruleus Noradrenergic System and its Role in Modulation of Neuroinflammation, Cognition, and Neurodegeneration

Locus coeruleus (LC) noradrenergic (NE) neurons supply the main adrenergic input to the forebrain. NE is a dual modulator of cognition and neuroinflammation. NE neurons of the LC are particularly vulnerable to degeneration both with normal aging and in neurodegenerative disorders. Consequences of th...

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Detalles Bibliográficos
Autores principales: Evans, Andrew K., Defensor, Erwin, Shamloo, Mehrdad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9748190/
https://www.ncbi.nlm.nih.gov/pubmed/36532725
http://dx.doi.org/10.3389/fphar.2022.1030609

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9748190/
https://www.ncbi.nlm.nih.gov/pubmed/36532725
http://dx.doi.org/10.3389/fphar.2022.1030609

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