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Domain-specific insight into the recognition of BH3-death motifs by the pro-survival Bcl-2 protein

Programmed mammalian cell death (apoptosis) is an essential mechanism in life that tightly regulates embryogenesis and removal of dysfunctional cells. In its intrinsic (mitochondrial) pathway, opposing members of the Bcl-2 (B cell lymphoma 2) protein family meet at the mitochondrial outer membrane (...

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Detalles Bibliográficos
Autores principales: Mushtaq, Ameeq Ul, Ådén, Jörgen, Ali, Katan, Gröbner, Gerhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9748362/
https://www.ncbi.nlm.nih.gov/pubmed/36325615
http://dx.doi.org/10.1016/j.bpj.2022.10.041