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Domain-specific insight into the recognition of BH3-death motifs by the pro-survival Bcl-2 protein
Programmed mammalian cell death (apoptosis) is an essential mechanism in life that tightly regulates embryogenesis and removal of dysfunctional cells. In its intrinsic (mitochondrial) pathway, opposing members of the Bcl-2 (B cell lymphoma 2) protein family meet at the mitochondrial outer membrane (...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Biophysical Society
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9748362/ https://www.ncbi.nlm.nih.gov/pubmed/36325615 http://dx.doi.org/10.1016/j.bpj.2022.10.041 |