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Brazilin from Caesalpinia sappan inhibits viral infection against PRRSV via CD163(ΔSRCR5) MARC-145 cells: an in silico and in vitro studies

This research aimed to identify bioactive compounds from Caesalpinia sappan extract that function as novel porcine reproductive and respiratory syndrome virus (PRRSV) infection inhibitors by computational molecular screening. We obtained a set of small-molecule compounds predicted to target the scav...

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Detalles Bibliográficos
Autores principales: Arjin, Chaiwat, Tateing, Suriya, Potapohn, Nuttha, Arunorat, Jirapat, Pringproa, Kidsadagon, Lumsangkul, Chompunut, Seel-audom, Mintra, Ruksiriwanich, Warintorn, Sringarm, Korawan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9748407/
https://www.ncbi.nlm.nih.gov/pubmed/36517668
http://dx.doi.org/10.1038/s41598-022-26206-x