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Targeting malaria parasites with novel derivatives of azithromycin

INTRODUCTION: The spread of artemisinin resistant Plasmodium falciparum parasites is of global concern and highlights the need to identify new antimalarials for future treatments. Azithromycin, a macrolide antibiotic used clinically against malaria, kills parasites via two mechanisms: ‘delayed death...

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Detalles Bibliográficos
Autores principales: Burns, Amy L., Sleebs, Brad E., Gancheva, Maria, McLean, Kimberley T., Siddiqui, Ghizal, Venter, Henrietta, Beeson, James G., O’Handley, Ryan, Creek, Darren J., Ma, Shutao, Frölich, Sonja, Goodman, Christopher D., McFadden, Geoffrey I., Wilson, Danny W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9748569/
https://www.ncbi.nlm.nih.gov/pubmed/36530422
http://dx.doi.org/10.3389/fcimb.2022.1063407