Proteomics analysis of the p.G849D variant in neurexin 2 alpha may reveal insight into Parkinson’s disease pathobiology

Parkinson’s disease (PD), the fastest-growing neurological disorder globally, has a complex etiology. A previous study by our group identified the p.G849D variant in neurexin 2 (NRXN2), encoding the synaptic protein, NRXN2α, as a possible causal variant of PD. Therefore, we aimed to perform function...

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Detalles Bibliográficos
Autores principales: Cuttler, Katelyn, Fortuin, Suereta, Müller-Nedebock, Amica Corda, Vlok, Maré, Cloete, Ruben, Bardien, Soraya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Aging Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9748613/
https://www.ncbi.nlm.nih.gov/pubmed/36533174
http://dx.doi.org/10.3389/fnagi.2022.1002777

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9748613/
https://www.ncbi.nlm.nih.gov/pubmed/36533174
http://dx.doi.org/10.3389/fnagi.2022.1002777

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