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In Chagas disease, transforming growth factor beta neutralization reduces Trypanosoma cruzi infection and improves cardiac performance

Chronic Chagasic cardiomyopathy (CCC), a progressive inflammatory and fibrosing disease, is the most prominent clinical form of Chagas disease, a neglected tropical disease caused by Trypanosoma cruzi infection. During CCC, the parasite remains inside the cardiac cells, leading to tissue damage, inv...

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Detalles Bibliográficos
Autores principales: Ferreira, Roberto Rodrigues, de Souza, Elen Mello, Vilar-Pereira, Glaucia, Degrave, Wim M. S., Abreu, Rayane da Silva, Meuser-Batista, Marcelo, Ferreira, Nilma Valéria Caldeira, Ledbeter, Steve, Barker, Robert H., Bailly, Sabine, Feige, Jean-Jacques, Lannes-Vieira, Joseli, de Araújo-Jorge, Tania C., Waghabi, Mariana Caldas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9748701/
https://www.ncbi.nlm.nih.gov/pubmed/36530434
http://dx.doi.org/10.3389/fcimb.2022.1017040