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The evolutionary dynamics that retain long neutral genomic sequences in face of indel deletion bias: a model and its application to human introns

Insertions and deletions (indels) of short DNA segments are common evolutionary events. Numerous studies showed that deletions occur more often than insertions in both prokaryotes and eukaryotes. It raises the question why neutral sequences are not eradicated from the genome. We suggest that this is...

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Detalles Bibliográficos
Autores principales: Loewenthal, Gil, Wygoda, Elya, Nagar, Natan, Glick, Lior, Mayrose, Itay, Pupko, Tal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9748784/
https://www.ncbi.nlm.nih.gov/pubmed/36514983
http://dx.doi.org/10.1098/rsob.220223