Integration of transcriptomics and metabolomics reveals the molecular mechanisms underlying the effect of nafamostat mesylate on rhabdomyolysis-induced acute kidney injury

Objective: To investigate the role and mechanisms of action of nafamostat mesylate (NM) in rhabdomyolysis-induced acute kidney injury (RIAKI). Methods: RIAKI rats were assigned into control group (CN), RIAKI group (RM), and NM intervention group (NM). Inflammatory cytokines and proenkephalin a 119–1...

Descripción completa

Detalles Bibliográficos
Autores principales: Guo, Wenli, Wang, Yu, Wu, Yuxuan, Liu, Jiang, Li, Ying, Wang, Jing, Ou, Santao, Wu, Weihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9748812/
https://www.ncbi.nlm.nih.gov/pubmed/36532745
http://dx.doi.org/10.3389/fphar.2022.931670

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9748812/
https://www.ncbi.nlm.nih.gov/pubmed/36532745
http://dx.doi.org/10.3389/fphar.2022.931670

Ejemplares similares