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Integration of transcriptomics and metabolomics reveals the molecular mechanisms underlying the effect of nafamostat mesylate on rhabdomyolysis-induced acute kidney injury

Objective: To investigate the role and mechanisms of action of nafamostat mesylate (NM) in rhabdomyolysis-induced acute kidney injury (RIAKI). Methods: RIAKI rats were assigned into control group (CN), RIAKI group (RM), and NM intervention group (NM). Inflammatory cytokines and proenkephalin a 119–1...

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Detalles Bibliográficos
Autores principales:	Guo, Wenli, Wang, Yu, Wu, Yuxuan, Liu, Jiang, Li, Ying, Wang, Jing, Ou, Santao, Wu, Weihua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9748812/ https://www.ncbi.nlm.nih.gov/pubmed/36532745 http://dx.doi.org/10.3389/fphar.2022.931670

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