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Mannosylated Polycations Target CD206(+) Antigen-Presenting Cells and Mediate T-Cell-Specific Activation in Cancer Vaccination

[Image: see text] Immunotherapy is deemed one of the most powerful therapeutic approaches to treat cancer. However, limited response and tumor specificity are still major challenges to address. Herein, mannosylated polycations targeting mannose receptor- are developed as vectors for plasmid DNA (pDN...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Bellato, Federica, Feola, Sara, Dalla Verde, Gloria, Bellio, Greta, Pirazzini, Marco, Salmaso, Stefano, Caliceti, Paolo, Cerullo, Vincenzo, Mastrotto, Francesca
Format: Online Artikel Text
Sprache:English
Veröffentlicht: American Chemical Society 2022
Online Zugang:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9748946/
https://www.ncbi.nlm.nih.gov/pubmed/36394394
http://dx.doi.org/10.1021/acs.biomac.2c00993