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Mannosylated Polycations Target CD206(+) Antigen-Presenting Cells and Mediate T-Cell-Specific Activation in Cancer Vaccination

[Image: see text] Immunotherapy is deemed one of the most powerful therapeutic approaches to treat cancer. However, limited response and tumor specificity are still major challenges to address. Herein, mannosylated polycations targeting mannose receptor- are developed as vectors for plasmid DNA (pDN...

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Détails bibliographiques
Auteurs principaux: Bellato, Federica, Feola, Sara, Dalla Verde, Gloria, Bellio, Greta, Pirazzini, Marco, Salmaso, Stefano, Caliceti, Paolo, Cerullo, Vincenzo, Mastrotto, Francesca
Format: Online Article Texte
Langue:English
Publié: American Chemical Society 2022
Accès en ligne:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9748946/
https://www.ncbi.nlm.nih.gov/pubmed/36394394
http://dx.doi.org/10.1021/acs.biomac.2c00993