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Mannosylated Polycations Target CD206(+) Antigen-Presenting Cells and Mediate T-Cell-Specific Activation in Cancer Vaccination

[Image: see text] Immunotherapy is deemed one of the most powerful therapeutic approaches to treat cancer. However, limited response and tumor specificity are still major challenges to address. Herein, mannosylated polycations targeting mannose receptor- are developed as vectors for plasmid DNA (pDN...

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Detalhes bibliográficos
Principais autores: Bellato, Federica, Feola, Sara, Dalla Verde, Gloria, Bellio, Greta, Pirazzini, Marco, Salmaso, Stefano, Caliceti, Paolo, Cerullo, Vincenzo, Mastrotto, Francesca
Formato: Online Atigo Texto
Idioma:English
Publicado em: American Chemical Society 2022
Acesso em linha:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9748946/
https://www.ncbi.nlm.nih.gov/pubmed/36394394
http://dx.doi.org/10.1021/acs.biomac.2c00993