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MCI-frcnn: A deep learning method for topological micro-domain boundary detection

Chromatin structural domains, or topologically associated domains (TADs), are a general organizing principle in chromatin biology. RNA polymerase II (RNAPII) mediates multiple chromatin interactive loops, tethering together as RNAPII-associated chromatin interaction domains (RAIDs) to offer a framew...

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Detalles Bibliográficos
Autores principales: Tian, Simon Zhongyuan, Yin, Pengfei, Jing, Kai, Yang, Yang, Xu, Yewen, Huang, Guangyu, Ning, Duo, Fullwood, Melissa J., Zheng, Meizhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9749004/
https://www.ncbi.nlm.nih.gov/pubmed/36531953
http://dx.doi.org/10.3389/fcell.2022.1050769