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Development of Squalene-Based Oil-in-Water Emulsion Adjuvants Using a Self-Emulsifying Drug Delivery System for Enhanced Antigen-Specific Antibody Titers

INTRODUCTION: A recombinant protein cannot induce sufficient immune response by itself. Various substances, including cytokine and mineral, have been used as adjuvants to enhance the immunogenicity and efficacy of vaccines; however, most of them induce excessive immune responses or exhibit cytotoxic...

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Detalles Bibliográficos
Autores principales: Chae, Ga-Eul, Kim, Dong Woo, Jin, Hyo-Eon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9749031/
https://www.ncbi.nlm.nih.gov/pubmed/36531114
http://dx.doi.org/10.2147/IJN.S379950